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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNMT
All Species:
28.79
Human Site:
Y286
Identified Species:
63.33
UniProt:
Q14749
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14749
NP_061833.1
295
32742
Y286
G
Q
T
Y
I
P
C
Y
F
I
H
V
L
K
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089876
295
32693
Y286
G
Q
A
Y
V
P
C
Y
F
I
H
V
L
K
R
Dog
Lupus familis
XP_532140
295
32695
Y286
G
Q
A
S
I
P
C
Y
F
I
H
V
L
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXF8
293
32657
Y284
G
Q
A
Y
V
P
C
Y
F
I
H
V
L
K
K
Rat
Rattus norvegicus
P13255
293
32531
Y284
G
Q
A
Y
V
P
C
Y
F
I
H
V
L
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508790
588
65253
Y579
G
Q
D
H
T
P
C
Y
F
I
H
V
L
K
R
Chicken
Gallus gallus
XP_001232829
531
58160
Y522
G
Q
A
H
V
P
C
Y
F
I
H
V
V
K
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997981
294
33227
Y285
A
G
G
E
P
P
C
Y
F
I
H
V
V
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650223
289
32665
I281
V
K
N
P
A
F
Y
I
H
L
I
E
K
P
Q
Honey Bee
Apis mellifera
XP_625210
292
33740
Y284
E
I
K
N
A
G
F
Y
I
H
V
M
E
K
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784229
290
32784
A282
H
V
D
T
E
D
T
A
Y
F
Q
H
V
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.6
96.2
N.A.
91.8
91.5
N.A.
39.6
38.9
N.A.
72.5
N.A.
56.9
57.9
N.A.
36.6
Protein Similarity:
100
N.A.
99.6
97.2
N.A.
95.5
95.9
N.A.
45.2
47
N.A.
83.3
N.A.
72.1
72.1
N.A.
53.2
P-Site Identity:
100
N.A.
86.6
86.6
N.A.
80
80
N.A.
80
66.6
N.A.
53.3
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
N.A.
93.3
86.6
N.A.
93.3
93.3
N.A.
86.6
93.3
N.A.
66.6
N.A.
20
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
46
0
19
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
73
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
0
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
10
10
0
0
0
0
0
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
10
10
0
73
10
0
0
0
0
0
% F
% Gly:
64
10
10
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
19
0
0
0
0
10
10
73
10
0
0
10
% H
% Ile:
0
10
0
0
19
0
0
10
10
73
10
0
0
0
0
% I
% Lys:
0
10
10
0
0
0
0
0
0
0
0
0
10
82
37
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
0
0
55
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
73
0
0
0
0
0
0
0
10
10
% P
% Gln:
0
64
0
0
0
0
0
0
0
0
10
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
37
% R
% Ser:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
10
10
0
10
0
0
0
0
0
0
0
0
% T
% Val:
10
10
0
0
37
0
0
0
0
0
10
73
28
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
37
0
0
10
82
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _